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Event overview information:

The 27th Annual Blood-Brain Barrier (BBB) Consortium Meeting, will be hosted by the Neuro-Oncology Program at Providence Brain and Spine Institute on May 15 and 16, 2025. The Scientific Advisory Board has assembled an outstanding group of speakers from a variety of disciplines with ample time for group discussions and networking. The event will take place at The Benson Hotel in Portland, Oregon.

Goals: The primary goal of this meeting is to foster translational interactions between scientists and clinicians focused on the BBB, the neuro-vascular unit (NVU), and specialized neural barriers in central nervous system (CNS) diseases. The aim is to translate basic and preclinical research advances into clinical trials in neuro-oncology.

A related goal is to disseminate meeting findings to the scientific community. Previous meetings have resulted in publications in the Journal of Cerebral Blood Flow & Metabolism, Nature Reviews Neuroscience, and Neuro-Oncology, as well as a chapter in Advances in Pharmacology.

Content: This meeting will highlight advancements in BBB Consortium clinical research, including new treatment and neuro-imaging protocols, and the translation of research from the lab to the clinic. Presentations by experts in neuro-oncology, neuro-infectious disease, neuro-immunology, neuro-cognitive science, and neuroimaging will be followed by group discussions, panel discussions, and poster sessions.

Objectives:

1.Breakdown of the NVU in Neuro-Oncology: Discuss preclinical, clinical, and safety data on techniques to enhance the delivery of therapeutic agents and systemic immune cell migration to brain tumors and the tumor microenvironment. This includes methods such as intra-arterial delivery and focused ultrasound.

2.Impact of the NVU in Neuro-Infectious Disease: Examine preclinical and clinical studies on neurological complications of systemic viral infections, including COVID-19. Topics include improving delivery methods, novel therapeutic and imaging modalities, and the need for chemoprotection.

3.Role of the NVU in Emerging Real-Life Scenarios: Explore the NVU’s role in scenarios with significant human health impacts, such as weightlessness and space exploration, climate change, and microplastic pollution.

Mentorship Session: The meeting will include mentoring sessions, providing young scientists and trainees with one-on-one time with senior mentors.

We are honored to welcome you and hope this meeting is both educational and engaging. We are grateful for your participation and look forward to many stimulating discussions.

For more information and registration: https://cmetracker.net/PPMC/Publisher?page=pubOpen#/custom1