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A NordicPOP sponsored event.

Venue: Rudbecksalen, Rudbecklab, Uppsala University, Uppsala, Sweden

Organizing committee:
Birger Brodin, Professor, University of Copenhagen;
Kristiina Huttunen, Associate Professor, University of Eastern Finland;
Margareta Hammarlund-Udenaes, Professor Emerita, Uppsala University;
Christoffer Bundgaard, Director, H. Lundbeck A/S.

Registration is mandatory, attendance is free.
Attendees are accepted on a first-come-first-serve basis (maximum number of participants is 130).
For registration click here.

Posters are welcome from PhD students. If so, please send an abstract (1 A4 page, standing PDF format) to This email address is being protected from spambots. You need JavaScript enabled to view it. and bring a poster (standing A0). We are not able to assist with travel and accommodation. Much welcome!

PROGRAM
08:30-09:00  Registration & coffee
09:00-09:15  Welcome from the organizers
SESSION 1: GLYMPHATICS – FACTS OR FICTION? 
09:15-09:45
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 Steven T. Proulx, University of Bern
 In vivo imaging of cerebrospinal fluid circulation and clearance in mice
09:45-10:15
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 Laura Bojarskaite, University of Oslo
 Cortical blood vessel dynamics during sleep in health and disease
10:15-10:45  Coffee and posters
SESSION 2: NEURODEGENERATION AND THE BBB 
 10:45-11:15
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 Dag Sehlin, Uppsala University
 Lecanemab interactions with amyloid-beta in the brain – implications for Alzheimer
therapy
11:45-12:15
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 Annakaisa Haapasalo, University of Eastern Finland, Kuopio
 Contribution of immune system alterations to the pathogenesis of frontotemporal
dementia
11:15-11:45
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 Pekka Kallunki, Lundbeck, Copenhagen
 Clinical dose selection for alpha synuclein-targeting antibodies based on target
protein binding levels in the brain and CSF and PKPD modelling
12:15-12:45
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 Helena Karlström, Karolinska Institute, Stockholm
 Vascular changes in CNS disease and treatment strategies
12:45-14:00  Lunch and poster session
SESSION 3: BEYOND THE BBB 
14:00-14:30
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 Irena Loryan, Uppsala University
 The role of central and peripheral nervous system barriers in the development and
treatment of chemotherapy-induced peripheral neuropathy
14:30-15:00
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 Heidi Kidron, University of Helsinki
 Impact of genetic variation on transporter activity
15:00-15:45  Coffee and posters
SESSION 4: BARRIER MODELING AND MECHANISTIC STUDIES 
15:45-16:15
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 Peetra Magnusson, Uppsala University
 Modelling cavernoma using patient-derived and engineered induced pluripotent
stem cells
16:15-16:45
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 Morten Schallburg Nielsen, Aarhus University
 In vitro transcytosis of antibody constructs
16:45-17:00  Goodbye from the organizers
17:00-18:30  Wine, snacks & networking outside the auditorium