Position Openings

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Postdoctoral position open at Texas Tech School of Pharmacy, Amarillo A postdoctoral position (one year, with option for second year) is available immediately in the lab of Ulrich Bickel, MD, Department of Pharmaceutical Sciences, Texas Tech University Health Sciences Center at Amarillo. Dr. Bickel's group focuses on blood-barrier transport mechanisms and drug delivery of macromolecules. The successful applicant will work on an innovative new project exploring the targeting of breast cancer metastasis in brain using a novel type of monoclonal antibody (J Cell Physiol 225:664-672; J Immunol 186: 3265-3276) funded by the Cancer Prevention and Research Institute of Texas (CPRIT). Background in pharmacology/ pharmaceutical sciences or related areas with experience in pharmacokinetic studies in rodents, cell culture and histological techniques, including (confocal) fluorescence microscopy, and basic molecular biology techniques is advantageous. Please submit applications with curriculum vitae, brief outline of accomplishments, research interests and career goals, and contact information for three references to Ulrich Bickel, M.D. Professor Department of Pharmaceutical Sciences Texas Tech University Health Sciences Center at Amarillo 1300 Coulter St. Amarillo, TX 79106. phone: (+1) 806.356.4015 ext. 336 fax: (+1) 806.356.4034 e-mail: Ulrich.Bickel@ttuhsc.edu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Research assistant position Women and Children, Brown Alpert Medical School Our laboratory is concerned with understanding the effects of brain ischemia on blood-brain barrier permeability to cytokines and potential anti-cytokine neuroprotective strategies using the fetal sheep and a neonatal rat models. The work will potentially yield neuroprotective strategies that will prevent the development of cerebral palsy in infants. Our exciting two year position includes participation in experiments in pregnant sheep and neonatal rats, which include surgical preparation, physiologic studies, molecular biological, immunohistochemical, immunological analysis in the fetal sheep and neonatal rat brains, computerized analysis of hemodynamic measures in the fetus, and EEG analysis of the fetal brain and computerized microscopic analysis of both neonatal rat and fetal sheep brain. This exciting neuroscience opportunity in an extremely productive laboratory will permit the research assistant opportunity for publication in prestigious peer review journals. The position requires BA, BS or MA degree preferably, familiarity with neuroscience in molecular and biologic, histological and microscopic approaches. Experience with laboratory bench work, data acquisition, statistical analysis and analytic microscopic work is preferred, but not required. These are an ideal position for a recent graduate willing to make a commitment for two years to funded NIH grants. For more information, contact Dr. Barbara Stonestreet at 274-1122, x7429 or Bstonestreet@wihri.org (email). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Postdoctoral Fellow in Athens, GA, US Dr. Jason Zastre is seeking to fill a postdoctoral fellow position in his lab at the University of Georgia,lege of Pharmacy, in Athens, GA, US. Part of the project would be on Brain Barriers work. A job description can be found here, and for more information, email Dr. Zastre at jzastre@rx.uga.edu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Sr. Scientist II position opening in Massachusetts Fidelis Biopharm is recruiting for a Sr. Scientist II in Massachusetts. The ideal candidate will have the following skills and interests: PhD, to play a leading role to investigate, identify, develop, and optimize new methods/ techniques in in vitro characterization of biologics Be proficient in establishing functional cell-based assay development for immunology and neuroscience projects Independent, self-motivated, and well organized Expertise in utilizing ECL, ELISA, FACS, tissue culture and molecular biology techniques are required Experience in receptor biology, protein internalization and transport mechanisms and blood-brain barrier targeting is preferred For more information, contact Dr. May Li at 972-770-7904 (office) or mli@fidelisbiopharm.com (email). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Postdoctoral Position Available at Temple University School of Medicine (Philadelphia PA) Postdoctoral position available in the laboratory of Dr. Yuri Persidsky. The successful candidate will investigate the properties and function of the BBB, as well as targeting of therapeutics to the BBB, in the context of HIV-1 encephalitis, alcohol and methamphetamine abuse. The candidate would also be involved in studies related to how the brain endothelium affects neural stem cells renewal and differentiation. The laboratory uses both in-vivo and in-vitro models for analysis of BBB function. Interested scientists should send a CV, list of references, and cover letter to: Yuri Persidsky, MD, PhD e-mail: yuri.persidsky@tuhs.temple.edu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Postdoctoral Position Available at Texas A&M College of Medicine, College Station, Texas A postdoctoral position is available in the laboratory of Gregory Bix, M.D., Ph.D.. This position is part of an NIH funded project involving the potential therapeutic effects of proteolytic extracellular matrix fragments in stroke. The Ideal candidate would be a recent Ph.D. or M.D./Ph.D. with a background in mice or rat stroke model surgeries and/or some experience with neuronal or brain endothelial cell culture. The candidate will also be expected to communicate findings with the research community in English and work effectively with graduate and undergraduate students. Detailed information can be found at http://medicine.tamhsc.edu/basic-sciences/mcm/faculty/gregory-bix.html Interested scientists should send a CV, list of references, and cover letter to gjbix@medicine.tamhsc.edu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Postdoctoral Position available at Pennington Biomedical Research Center, Louisiana, USA The Pennington Biomedical Research Center, a research facility of the Louisiana State University System, is seeking a qualified applicant for a postdoctoral research position in the Blood-Brain Barrier Laboratory. The NIH-funded projects address the regulations and functions of astrocytic leptin signaling in mouse models of obesity and neuroinflammation. For more details, please refer to http://labs.pbrc.edu/bloodbrainbarrier. Duties will involve conducting research projects on protein trafficking, CNS trauma, inflammation, ischemia, neurodegeneration, and sleep. Techniques related to cell biology, microsurgery, neuroanatomy, immunohistochemistry, whole animal physiology, and pharmacology are desired. The candidate is expected to be honest, intelligent, flexible, technically competent, interactive with others in a research team, able to communicate findings with the research community in English, and truly interested in neuroscience. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PhD Position Available Gardanne, France Position: PhD position to integrate live cells with organic electrochemical transistors to develop an in vitro blood brain barrier model (funded by the European Research Council (ERC)) Start date: October 1st 2011 For more information: Job Announcement owens@emse.fr . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Postdoctoral Position Available at University of Wisconsin-Madison A postdoctoral position is available in the laboratory of Professor Eric Shusta. This position is part of an NIH-funded project involving the development of a human pluripotent stem cell-derived blood brain barrier model. This model will be used in drug permeability screening, studies of blood-brain barrier development, and studies of blood-brain barrier regulation. Detailed information can be found here, for more information. Ideal candidates would possess a solid blood-brain barrier background as well as skill sets in cell and molecular biological approaches. Capabilities in stem cell biology would be an additional plus. Interested scientists should send a CV, list of references, and cover letter to shusta@engr.wisc.edu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Post-Doctoral Research Associate Position Available at The Open University A PDRA position is available to start in early 2011 to work on microRNAs in the cerebral vasculature in neuroinflammation funded by the MS Society. Click here, for more information. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Ph.D. Student Opportunity at the Theodor Kocher Institute, University of Bern For further information, see flyer. Interested applicants are invited to send their letter of motivation, CV, certificates and 2 letters of reference via E-mail to Prof. Britta Engelhardt (bengel@tki.unibe.ch). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Amsterdam - Two PhD-Student Positions available Two PhD-student positions are available in MS research in Amsterdam. Come and join the stimulating environment of a leading MS Center. More information regarding the two research projects are below: 1. Project title: "Unravel molecular mechanisms underlying MS pathology: mitochondrial stress and astrocyte responses." For more information, click on this link: http://www.ibbsoc.org/PhD_position_de_Vries_MS_Research1.pdf Or please contact Dr. Jack van Horssen (j.vanhorssen@vumc.nl) or Dr. Elga de Vries (he.devries@vumc.nl). Applications should include a CV and suggested references and can be e-mailed to he.devries@vumc.nl. 2. Project title: "Halting neurodegeneration in MS: taking control of the neurovasculature." For more information, click on this link: http://www.ibbsoc.org/PhD_position_de_Vries_MS_Research2.pdf Or please contact Dr. Arie Reijerkerk(a.reijerkerk@vumc.nl) or Dr. Elga de Vries (he.devries@vumc.nl). Applications should include a CV and suggested references and can be e-mailed to he.devries@vumc.nl. .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . NIH-NINDS, US - Program Director Position A program director position in stroke currently open at NINDS. For further information, see flyer or contact Dr. Robert Finkelstein at finkelsr@ninds.nih.gov. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . New Orleans, LA, US - Post Doctoral Position A post-doc position in Dr. Manus Maclean's Lab will open up in the next couple of months looking at signal transduction in endothelial cells in HIV neuropathogenesis. Candidates should have, or be about to get, a PhD in neuroscience, cell biology, molecular biology or related field. Good interpersonal skills are a must, as is ability to work independently. For further information, please email: amaclean@tulane.edu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Rhode Island, US - Post Doctoral Position A Post-doctoral Position is available in the Perinatal Brain Research laboratory of Barbara S. Stonestreet, M.D. in the Department of Pediatrics at Women & Infants Hospital of Rhode Island to define the effects of brain ischemia on blood-brain barrier permeability to cytokines and potential anti-cytokine neuroprotective strategies using the fetal sheep model during development. More info: here. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Lyon, France - Post Doctoral Position Dr. Jean-Francois Ghersi-Egea's team is seeking a post doctoral researcher. More info: here. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . University of Minnesota - Tenure Track Position The Department of Pharmacy Practice and Pharmaceutical Sciences, College of Pharmacy, at the University of Minnesota, invites applications and nominations for the position of Assistant Professor (tenure-track) or Associate Professor (tenured or tenure-track) specializing in central nervous system (CNS) clinical pharmacology. More info: here. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Paris, France - Post Doctoral Position The Neuropsycopharmacology of Drug Addiction and Department of Pharmaceutical Sciences is seeking a post doctoral researcher. More info: here. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Academic position: Blood Brain Barrier Specialist Copenhagen Research Scientist The Department of Biologics within the division of Discovery Biology Research at Lundbeck A/S is looking for a research scientist with a strong background in the area blood brain barrier research (BBB). This is a unique opportunity for an up and coming Ph.D. scientist to lead a research effort aimed at designing novel drug delivery vehicle for protein based drugs across the blood brain barrier. More info: here.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Italy - Postdoctoral Position Opening A postdoctoral position is available in Dr. Ugo Cavallaro's laboratory at the IFOM-IEO Campus, in Milan, Italy. More info: here.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . USA - NIH Postdoctoral Position Opening A postdoctoral position is available in Dr. David Miller's group in the Laboratory of Pharmacology, National Institute of Environmental Health Sciences, National Institutes of Health in Research Triangle Park, NC to study mechanisms of regulation of ABC transporters (p-glycoprotein, Mrp2, Mrp4, BCRP) at the blood-brain barrier. The group is looking at ways to modify the barrier to improve CNS pharmacotherapy. We are concerned about how the barrier changes in CNS disease and how those changes alter the ability to deliver therapeutic drugs to the brain. Our experiments are done in vivo with mice and rats and in vitro with intact, functional brain capillaries. We are currently developing ways to apply molecular biological techniques to those systems and to better image blood-brain barrier transport and signaling in vivo using optical probes and multiphoton microscopy.The ideal candidate would be a recent Ph.D. or Pharm. D with a background in transport biology or signaling. Starting date is flexible. Interested scientists should send a CV and a cover letter to Dr. Miller (miller@niehs.nih.gov). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .